Use of a physiological reflex to standardize vagal nerve stimulation intensity improves data reproducibility in a memory extinction assay
Background: Modulating brainstem activity, via electrical vagus nerve stimulation (VNS), influences cognitive functions, including memory.However, controlling for changes in stimulus efficacy during chronic studies, and response variability between subjects, is problematic.Objective/Hypothesis: We hypothesized that recruitment of an autonomic refle